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Liver is an important organ as it performs vital metabolic functions. The liver function is affected by various conditions including unhealthy lifestyles. The impact of liver diseases has increased worldwide. The healthcare professionals are increasingly encountering patients with liver issues.
Silymarin, a flavonolignan from 'milk thistle' (Silybum marianum) is used from ancient times as a hepatoprotective drug. It stimulates liver tissue regeneration by increasing protein synthesis in the injured liver. As an antioxidant, silymarin increases superoxide dismutase (SOD) activity of lymphocytes and erythrocytes. It also has anti-lipid peroxidative, antifibrotic, anti-inflammatory, membrane stabilizing and immunomodulatory properties.